DNA Binding Motif

						

			
Accessions: 1hcq_EF (3D-footprint 20231221)

			
Names: PROTEIN (ESTROGEN RECEPTOR)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: THE CRYSTAL STRUCTURE OF THE ESTROGEN RECEPTOR DNA-BINDING DOMAIN BOUND TO DNA: HOW RECEPTORS DISCRIMINATE BETWEEN THEIR RESPONSE ELEMENTS
Length: 13
Consensus: GGTCAnnnTGACC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0      0     96      0      G
03      0     20      6     70      T
04      0     96      0      0      C
05     68      9      6     13      A
06     24     24     24     24      n
07     24     24     24     24      n
08     24     24     24     24      n
09      9      6     13     68      T
10      0      0     96      0      G
11     78      6      6      6      A
12      0     96      0      0      C
13      0     96      0      0      C
Type: Heterodimer
Binding TFs: 1hcq_E (Zinc finger, C4 type (two domains))
1hcq_F (Zinc finger, C4 type (two domains))
Binding Sites: 1hcq_G
1hcq_H
			
Publications: Schwabe J. W. R., Chapman L., Finch J. T., Rhodes D. The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements. Cell 75:567-578 (1993). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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