DNA Binding Motif

Accessions: MA0063.3 (JASPAR 2024)
Names: NKX2-5
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 7
Consensus: CACTCAA
Weblogo:
PSSM: P0 A C G T
01 96 5002 24 322 C
02 5246 48 76 74 A
03 144 5098 49 153 C
04 135 82 61 5166 T
05 222 4319 62 841 C
06 4819 120 217 288 A
07 4931 165 98 250 A
Type: Heterodimer
Binding TFs: P52952 (Homeobox domain)
P52952
Binding Sites: MA0063.3.1 / MA0063.3.10 / MA0063.3.11 / MA0063.3.16 / MA0063.3.19 / MA0063.3.2 / MA0063.3.3 / MA0063.3.6 / MA0063.3.9
MA0063.3.12
MA0063.3.13
MA0063.3.14 / MA0063.3.20 / MA0063.3.5 / MA0063.3.7
MA0063.3.15
MA0063.3.17
MA0063.3.18
MA0063.3.4
MA0063.3.8
Publications: Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.