DNA Binding Motif

Accessions: UP00067A_2 (UniPROBE 20160601)
Names: 3000002B05, AI451430, Lef-1, Lef1, lymphoid enhancer binding factor 1, lymphoid enhancer factor 1, Lymphoid enhancer-binding factor 1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: swrsATCAATCrctww
Weblogo:
PSSM: P0 A C G T
01 0.23 0.27 0.39 0.11 s
02 0.44 0.08 0.23 0.25 w
03 0.42 0.14 0.32 0.12 r
04 0.17 0.34 0.39 0.10 s
05 0.81 0.02 0.01 0.16 A
06 0.04 0.01 0.01 0.94 T
07 0.02 0.90 0.04 0.04 C
08 0.94 0.01 0.01 0.04 A
09 0.93 0.01 0.04 0.02 A
10 0.03 0.02 0.05 0.91 T
11 0.11 0.71 0.01 0.17 C
12 0.68 0.02 0.28 0.03 r
13 0.24 0.35 0.19 0.23 c
14 0.09 0.24 0.20 0.46 t
15 0.33 0.18 0.11 0.38 w
16 0.34 0.16 0.19 0.32 w
Binding TFs: UP00067A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Binding Sites: AATCAAAG
ACATCAAA
ACTTCAAA
ACTTTGAT
AGATCAAA
AGATCAAT
ATCAAAAG
ATCAAAGA
ATCAAAGC
ATCAAAGG
CATCAAAG
CCTTTGAA
CTTCAAAG
CTTTGAAC
CTTTGATA
GATCAAAA
GCCTTTGA
GGATCAAA
TGATCAAA
CTTTCATC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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