DNA Binding Motif

						

			
Accessions: HOXB13_EOMES_1 (HumanTF2 1.0)

			
Names: HOXB13_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: aggTGtswmATwAAa
Weblogo: 
PSSM: P0      A      C      G      T
01    486     96    217    153      a
02    110     88    188    100      g
03     70     97    486     91      g
04     32    117     20    486      T
05     21      7    486     24      G
06    210    127    139    486      t
07     81    239    247    158      s
08    132    120     66    169      w
09    185    187      7    108      m
10    486     18     98     63      A
11     43     29     23    486      T
12    486     29     41    225      w
13    486      6     17     86      A
14    486     89     43     90      A
15    219     90     71    107      a
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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