DNA Binding Motif

						

			
Accessions: 5z2t_CD (3D-footprint 20231221)

			
Names: Double homeobox protein 4
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of DNA-bound DUX4-HD2
Length: 8
Consensus: TTAsaTTA
Weblogo: 
PSSM: P0      A      C      G      T
01      4      4      4     84      T
02      9      9      9     69      T
03     88      2      2      4      A
04     22     25     27     22      s
05     49     15     17     15      a
06      1      1      2     92      T
07      9      9     11     67      T
08     96      0      0      0      A
Type: Heterodimer
Binding TFs: 5z2t_C (Homeobox domain, Homeobox KN domain)
5z2t_D (Homeobox domain, Homeobox KN domain)
Binding Sites: 5z2t_E
5z2t_F
			
Publications: Dong X, Zhang W, Wu H, Huang J, Zhang M, Wang P, Zhang H, Chen Z, Chen SJ, Meng G. Structural basis of DUX4/IGH-driven transactivation. Leukemia : (2018). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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