DNA Binding Motif

						

			
Accessions: IRF8_methyl_1 (HT-SELEX2 May2017)

			
Names: IRF8
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Length: 15
Consensus: ryGAAAsyGAAAsyr
Weblogo: 
PSSM: P0      A      C      G      T
01    696    526    606    482      r
02    307   1500    243    810      y
03    260     33   2309     64      G
04   2309    171     77     79      A
05   2309     40    119    401      A
06   2309     45      0    120      A
07    132   1493    816     82      s
08     76   1156     41   1153      y
09    128      7   2309     18      G
10   2309    260     63     81      A
11   2309     67    245    562      A
12   2309     67     18    158      A
13    123   1666    644     86      s
14    406   1040    184   1270      y
15    847    425    663    374      r
Binding TFs: IRF8 (Interferon regulatory factor transcription factor)
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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