DNA Binding Motif

						

			
Accessions: FOXE1_2 (HT-SELEX2 May2017), MA1487.1 (JASPAR 2024)

			
Names: FOXE1
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 15
Consensus: cvyTAARyAAACAay
Weblogo: 
PSSM: P0      A      C      G      T
01     54    289    165    155      c
02    288    381    283      0      v
03     37    298     38    366      y
04    191      0      0    664      T
05    664     15     30      0      A
06    664     57     58    194      A
07    664      0    228      0      R
08      0    324      0    340      y
09    664     10      0      0      A
10    664      8      0      0      A
11    664      0      0      0      A
12      0    664      0      0      C
13    664      0      3      0      A
14    521     84    123    142      a
15    148    180    100    235      y
Type: Heterodimer
Binding TFs: FOXE1 (Fork head domain)
O00358 (Fork head domain)
O00358
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]


Fernández LP, López-Márquez A, Martínez AM, Gómez-López G, Santisteban P. New insights into FoxE1 functions: identification of direct FoxE1 targets in thyroid cells. PLoS One : (2013). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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