DNA Binding Motif

Accessions: 1vkx_AB (3D-footprint 20231221)
Names: PROTEIN (NF-KAPPA B P65 SUBUNIT)
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE NFKB P50/P65 HETERODIMER COMPLEXED TO THE IMMUNOGLOBULIN KB DNA
Length: 11
Consensus: GGAanGTCCCa
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 96 0 G
03 96 0 0 0 A
04 64 12 10 10 a
05 24 24 24 24 n
06 0 0 96 0 G
07 0 1 21 74 T
08 0 96 0 0 C
09 0 96 0 0 C
10 0 96 0 0 C
11 53 12 10 21 a
Type: Heterodimer
Binding TFs: 1vkx_A (Rel homology domain (RHD))
1vkx_B (Rel homology domain (RHD))
Binding Sites: 1vkx_C
1vkx_D
Publications: Chen F.E, Huang D.B, Chen Y.Q, Ghosh G. Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA. Nature 391:410-3 (1998). [Pubmed]

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