DNA Binding Motif

						

			
Accessions: ETV2_SOX15_2_3 (HumanTF2 1.0)

			
Names: ETV2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rCCGGAWGyamrmACAAwrg
Weblogo: 
PSSM: P0      A      C      G      T
01    816    114    406     94      r
02    100    961    261     65      C
03    114   1222     36      9      C
04      4      0   1222      0      G
05      3      1   1222      0      G
06   1222     12      8      0      A
07    885     36      0    337      W
08    292     37    907      0      G
09    135    385    132    570      y
10    465    257    275    226      a
11    455    387    129    251      m
12    405    120    608     89      r
13    572    312    239     98      m
14   1222     26     49     53      A
15     17   1222     50    140      C
16   1222     47     33     44      A
17   1222     19     27     53      A
18    617     13      2   1222      w
19    647    175    575     69      r
20    137    234    749    102      g
Type: Heterodimer
Binding TFs: SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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