DNA Binding Motif

Accessions: ELK1_HOXA3_1 (HumanTF2 1.0)
Names: ELK1_HOXA3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 24
Consensus: aCCGGwAAtkrkwyywcycATTAc
Weblogo:
PSSM: P0 A C G T
01 525 22 125 123 a
02 66 795 139 9 C
03 94 795 11 4 C
04 12 21 795 21 G
05 0 28 795 0 G
06 453 28 0 342 w
07 663 10 38 84 A
08 655 31 69 39 A
09 26 169 69 531 t
10 76 46 269 403 k
11 227 86 426 56 r
12 138 135 260 263 k
13 356 78 139 222 w
14 60 213 84 439 y
15 142 310 58 285 y
16 429 76 60 230 w
17 132 428 101 135 c
18 180 502 293 336 y
19 369 795 337 170 c
20 795 78 229 58 A
21 32 58 32 795 T
22 73 186 66 795 T
23 795 60 96 199 A
24 194 341 174 86 c
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
ELK1_TF1 (Ets-domain)
HOXA3_TF1 / HOXA3_TF2 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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