DNA Binding Motif

						

			
Accessions: 3lap_AD (3D-footprint 20231221)

			
Names: Arginine repressor
Organisms: Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: The Structure of the Intermediate Complex of the Arginine Repressor from Mycobacterium tuberculosis Bound to its DNA Operator and L-canavanine.
Length: 13
Consensus: GCATCnnTATGCA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0     96      0      G
02      0     96      0      0      C
03     78      6      6      6      A
04      0      0      0     96      T
05      6     78      6      6      C
06     24     24     24     24      n
07     24     24     24     24      n
08      6      6      6     78      T
09     96      0      0      0      A
10      6      6      6     78      T
11      0      0     96      0      G
12      0     96      0      0      C
13     78      6      6      6      A
Type: Heterodimer
Binding TFs: 3lap_D (Arginine repressor, DNA binding domain, Arginine repressor, C-terminal domain)
3lap_A (Arginine repressor, DNA binding domain, Arginine repressor, C-terminal domain)
Binding Sites: 3lap_K
3lap_L
			
Publications: Cherney L.T, Cherney M.M, Garen C.R, James M.N. Crystal structure of the intermediate complex of the arginine repressor from Mycobacterium tuberculosis bound with its DNA operator reveals detailed mechanism of arginine repression. Journal of molecular biology 399:240-54 (2010). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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