DNA Binding Motif

Accessions: ELK1_EOMES_1 (HumanTF2 1.0)
Names: ELK1_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 29
Consensus: rrGyGygrrrryrgkrtsrCrCCGGAAgy
Weblogo:
PSSM: P0 A C G T
01 852 448 566 247 r
02 760 428 1352 465 r
03 106 266 1464 117 G
04 62 756 110 1408 y
05 26 3 1530 19 G
06 281 460 209 580 y
07 313 681 1347 778 g
08 1439 109 644 232 r
09 510 353 536 131 r
10 468 215 489 357 r
11 385 315 449 381 r
12 211 402 373 543 y
13 547 199 469 316 r
14 346 306 584 293 g
15 213 262 561 494 k
16 429 216 565 320 r
17 248 507 237 1431 t
18 299 527 536 168 s
19 552 166 525 287 r
20 35 1476 34 74 C
21 1474 22 940 4 r
22 121 1491 310 74 C
23 330 1492 24 0 C
24 1 1 1530 0 G
25 0 0 1530 1 G
26 1530 12 1 31 A
27 1394 79 0 470 A
28 493 353 1347 26 g
29 237 628 295 857 y
Type: Heterodimer
Binding TFs: ELK1_TF2 (Ets-domain)
ELK1_Full (Ets-domain)
EOMES_TF2 (T-box)
ELK1_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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