DNA Binding Motif

						

			
Accessions: PAX1_DBD (HumanTF 1.0), MA0779.1 (JASPAR 2024)

			
Names: PAX1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 17
Consensus: sGTCACGCwTSAsTGmm
Weblogo: 
PSSM: P0      A      C      G      T
01    314   3157   1423    327      s
02      3      0   5266     79      G
03    234     80      0   4396      T
04      3   4490      1    475      C
05   3574    213      2      0      A
06      2   4489      0    651      C
07      3      2   5304      3      G
08      0   4404   1017      0      C
09   2215     81     43   1529      w
10     11    425      2   4290      T
11      1   1769   4652     54      S
12   3579      2    595      0      A
13    824   1629   1230    744      s
14     74    612     32   4185      T
15    849     11   4289    880      G
16   1453   2561   1147      0      m
17   2643   2136    780   1290      m
Type: Heterodimer
Binding TFs: PAX1_DBD ('Paired box' domain, Homeodomain-like domain)
P15863 ('Paired box' domain, Homeodomain-like domain)
P15863
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Wolf LV, Yang Y, Wang J, Xie Q, Braunger B, Tamm ER, Zavadil J, Cvekl A. Identification of pax6-dependent gene regulatory networks in the mouse lens. PLoS One : (2009;4(1):e4159.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.