DNA Binding Motif

						

			
Accessions: 4kfc_AB (3D-footprint 20231221)

			
Names: KDP operon transcriptional regulatory protein KdpE
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of a hyperactive mutant of response regulator KdpE complexed to its promoter DNA
Length: 18
Consensus: TGTAAaannnnTnnaAAA
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      4      1     90      1      G
03      4      1      1     90      T
04     96      0      0      0      A
05     90      3      3      0      A
06     58      5     20     13      a
07     64      5     14     13      a
08     24     24     24     24      n
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12      0      0      0     96      T
13     24     24     24     24      n
14     24     24     24     24      n
15     64      8     11     13      a
16     96      0      0      0      A
17     90      3      2      1      A
18     82     13      0      1      A
Type: Heterodimer
Binding TFs: 4kfc_A (Response regulator receiver domain, Transcriptional regulatory protein, C terminal)
4kfc_B (Response regulator receiver domain, Transcriptional regulatory protein, C terminal)
Binding Sites: 4kfc_Y
4kfc_Z
			
Publications: Narayanan A, Kumar S, Evrard A.N, Paul L.N, Yernool D.A. An asymmetric heterodomain interface stabilizes a response regulator-DNA complex. Nature communications 5:3282 (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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