DNA Binding Motif

						

			
Accessions: MA1546.2 (JASPAR 2024)

			
Names: PAX3
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 14
Consensus: sGTCACGsywATTA
Weblogo: 
PSSM: P0      A      C      G      T
01    112    880    464    167      s
02      1      2   1344    126      G
03    181     79      6   1344      T
04      9   1344     23    263      C
05   1344      2     19      2      A
06     13   1344      2    201      C
07    161      1   1344      0      G
08      3    836    508      6      s
09    197    414    127    606      y
10    512    228    138    467      w
11   1344    152    353     86      A
12     50     43     24   1344      T
13     83    138     52   1344      T
14   1344     66    108    215      A
Type: Heterodimer
Binding TFs: P23760 (Homeobox domain, 'Paired box' domain, Paired box protein 7 )
P23760
			
Publications: Epstein JA, Song B, Lakkis M, Wang C. Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor. Mol Cell Biol 18:4118-30 (1998). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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