DNA Binding Motif

						

			
Accessions: HOXD12_TBX21_2 (HumanTF2 1.0)

			
Names: HOXD12_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 30
Consensus: rgGYGtkdkkcgkyktwmaCAssTmrTaAa
Weblogo: 
PSSM: P0      A      C      G      T
01   1000     50    579    158      r
02    830    414   1787    603      g
03     19    529   1787    154      G
04     16    804      9   1787      Y
05     56      4   1787      0      G
06    668    680    303   1787      t
07    187    406    668    525      k
08    607     43    513    624      d
09    416     75    715    582      k
10    325    329    611    522      k
11    225    712    415    436      c
12    387    353    651    397      g
13    135    391    698    564      k
14    132    646    226    783      y
15    197    306    796    488      k
16    290    297    313    887      t
17    532    263    106    886      w
18    684    651    295    157      m
19   1013    231    422    121      a
20     40   1787     18    269      C
21   1787     15    409     57      A
22    101   1787    813     24      s
23    383    658    512    234      s
24    112    289     69   1787      T
25    616    852    154    164      m
26    807    117    700    162      r
27    158     63     23   1787      T
28   1301    296    125    487      a
29   1787     34     67    303      A
30    841    303    211    432      a
Type: Heterodimer
Binding TFs: HOXD12_TF1 (Homeobox domain)
TBX21_TF2 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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