DNA Binding Motif

						

			
Accessions: ETV5_CLOCK (HumanTF2 1.0)

			
Names: ETV5_CLOCK
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rCACGTGkdggrsCGGAwgy
Weblogo: 
PSSM: P0      A      C      G      T
01    205    100    243     56      r
02     76    605     30      5      C
03    605     10     85     18      A
04      4    605     19    146      C
05     43     18    605      0      G
06     23     86     32    605      T
07     11     16    605     57      G
08     25    143    194    242      k
09    156    137    152    159      d
10    145    102    223    135      g
11    126     98    252    129      g
12    188     42    255    120      r
13    131    307    298     58      s
14    123    605     71      9      C
15      2      2    605      5      G
16      4      0    605     23      G
17    605      0     17     25      A
18    403     29     42    201      w
19    145    115    460      0      g
20     32    213    143    217      y
Type: Heterodimer
Binding TFs: CLOCK_TF1 / CLOCK_TF2 (Helix-loop-helix DNA-binding domain)
ETV5_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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