DNA Binding Motif

						

			
Accessions: ZNF174_2 (HT-SELEX2 May2017), UN0164.1 (JASPAR 2024)

			
Names: ZNF174
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 16
Consensus: kGsCrrTCACTyGcCa
Weblogo: 
PSSM: P0      A      C      G      T
01    162    120    267    251      k
02     69     35    682    116      G
03    142    294    225    139      s
04      5    797      7      5      C
05    297     79    484      4      r
06    652      3    403      0      r
07      0     12      2    801      T
08      3    801      0      8      C
09    795      0      7      7      A
10    105    718      0    164      C
11     15     48    115    728      T
12      1    385     46    410      y
13      0      0    792     13      G
14    109    433    197     62      c
15     29    767      0     24      C
16    342    193    110    156      a
Type: Heterodimer
Binding TFs: ZNF174 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q15697 (Zinc finger, C2H2 type, SCAN domain, Zinc-finger double domain, C2H2-type zinc finger)
Q15697
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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