DNA Binding Motif

Accessions: 3brd_A (3D-footprint 20231221)
Names: Lin-12 and glp-1 phenotype protein 1, isoform a
Organisms: Caenorhabditis elegans
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, P212121
Length: 5
Consensus: TGGGa
01 0 10 10 76 T
02 0 0 96 0 G
03 10 10 66 10 G
04 0 0 96 0 G
05 64 12 10 10 a
Binding TFs: 3brd_A (IPT/TIG domain, Beta-trefoil DNA-binding domain, LAG1, DNA binding)
Binding Sites: 3brd_B
Publications: Friedmann D.R, Wilson J.J, Kovall R.A. RAM-induced allostery facilitates assembly of a notch pathway active transcription complex. The Journal of biological chemistry 283:14781-91 (2008). [Pubmed]

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