DNA Binding Motif

						

			
Accessions: MYBL1_TBX21 (HumanTF2 1.0), UN0574.1 (JASPAR 2024)

			
Names: MYBL1_TBX21, MYBL1::TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1, JASPAR 2024 2
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX, HT-SELEX
Length: 14
Consensus: aGGTGTGACsGTTr
Weblogo: 
PSSM: P0      A      C      G      T
01   4064    175   1447    400      a
02    470    331   4455    320      G
03     57     64   4767    113      G
04     47    263    143   4724      T
05     65      9   4776     54      G
06    212    306    196   4569      T
07     91     74   4712    221      G
08   4426     22    302     39      A
09    719   4408    172    125      C
10    859   2329   2000    121      s
11     41     26   4794      5      G
12     66     81    245   4692      T
13     79     20    129   4746      T
14   1851    144   2332   1345      r
Type: Heterodimer
Binding TFs: MYBL1_TF1 (Myb-like DNA-binding domain, Myb-like DNA-binding domain)
TBX21_TF2 (T-box)
Q9UL17 (T-box)
Q9UL17
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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