DNA Binding Motif

						

			
Accessions: 1io4_ABC (3D-footprint 20231221)

			
Names: CAAT/ENHANCER BINDING PROTEIN BETA
Organisms: Homo sapiens, Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF RUNX-1/AML1/CBFALPHA RUNT DOMAIN-CBFBETA CORE DOMAIN HETERODIMER AND C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE CSF-1R PROMOTER
Length: 17
Consensus: TTTCCAAAnnnTGTGGT
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      5     15      6     70      T
03      0      0      0     96      T
04      0     96      0      0      C
05     11     75      5      5      C
06     80      5      5      6      A
07     96      0      0      0      A
08     86      5      5      0      A
09     24     24     24     24      n
10     24     24     24     24      n
11     24     24     24     24      n
12      1      5      5     85      T
13      0      0     96      0      G
14      0      0      0     96      T
15      0      0     96      0      G
16      0      0     96      0      G
17      6      5     10     75      T
Type: Heterodimer
Binding TFs: 1io4_C (Runt domain)
1io4_A (bZIP transcription factor, Basic region leucine zipper)
1io4_B (bZIP transcription factor, Basic region leucine zipper)
Binding Sites: 1io4_E
1io4_F
			
Publications: Tahirov T.H, Inoue-Bungo T, Morii H, Fujikawa A, Sasaki M, Kimura K, Shiina M, Sato K, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell 104:755-67 (2001). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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