DNA Binding Motif

						

			
Accessions: 5iyd_M (3D-footprint 20231221)

			
Names: Transcription initiation factor IIB
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Human core-PIC in the initial transcribing state (no IIS)
Length: 15
Consensus: TTTTnttnTTTnntT
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      0      0      0     96      T
03      0      0      0     96      T
04      0      0      0     96      T
05     24     24     24     24      n
06     11     11     11     63      t
07     13     16     11     56      t
08     24     24     24     24      n
09      7      5      5     79      T
10      0      0      0     96      T
11      0      0      0     96      T
12     24     24     24     24      n
13     24     24     24     24      n
14     11     11     12     62      t
15      0      0      0     96      T
Binding TFs: 5iyd_M (Cyclin, N-terminal domain, Transcription factor TFIIB repeat, TFIIB zinc-binding)
Binding Sites: 5iyd_X
5iyd_Y
			
Publications: He Y, Yan C, Fang J, Inouye C, Tjian R, Ivanov I, Nogales E. Near-atomic resolution visualization of human transcription promoter opening. Nature 533:359-65 (2016). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.