DNA Binding Motif

						

			
Accessions: UP00539A_3 (UniPROBE 20160601)

			
Names: AW546128, GLI-Kruppel family member GLI2, Gli2, Zinc finger protein GLI2
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 23
Consensus: rytmyyagCCyCCCACgtyrksk
Weblogo: 
PSSM: P0      A      C      G      T
01   0.54   0.15   0.27   0.03      r
02   0.06   0.59   0.09   0.26      y
03   0.21   0.05   0.15   0.59      t
04   0.42   0.28   0.10   0.21      m
05   0.17   0.48   0.07   0.28      y
06   0.08   0.35   0.06   0.51      y
07   0.65   0.08   0.05   0.22      a
08   0.20   0.16   0.62   0.02      g
09   0.14   0.75   0.03   0.08      C
10   0.07   0.86   0.04   0.03      C
11   0.24   0.36   0.10   0.30      y
12   0.02   0.88   0.08   0.02      C
13   0.17   0.80   0.01   0.02      C
14   0.12   0.73   0.01   0.13      C
15   0.76   0.04   0.10   0.11      A
16   0.02   0.77   0.07   0.13      C
17   0.15   0.22   0.47   0.16      g
18   0.24   0.18   0.18   0.41      t
19   0.22   0.26   0.23   0.28      y
20   0.25   0.04   0.55   0.16      r
21   0.17   0.08   0.46   0.28      k
22   0.12   0.29   0.45   0.14      s
23   0.09   0.11   0.53   0.28      k
Binding TFs: UP00539A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: ACCCCCCA
CCCCCCAC
GACCCCCC
GCCACCCA
GCCCACCC
GGACCCCC
ACCACCCA
AGACCACC
AGGCCACC
AGGTGGTC
CCACCCAC
CCACCCAG
CGACCACC
CGGTGGTC
GACCACCA
GACCACCC
GACCTCCC
GGACCACC
GGCCACCC
GGGCCACC
			
Publications: Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, McMahon AP. Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Genes Dev 26:2802-16 (2012). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.