DNA Binding Motif

						

			
Accessions: HOXB13_TBX21_1 (HumanTF2 1.0)

			
Names: HOXB13_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 18
Consensus: AgGTGTGAttkmwWAAAc
Weblogo: 
PSSM: P0      A      C      G      T
01    475     22     22     78      A
02     94      9    382     83      g
03     26     40    475     32      G
04      0     47     51    475      T
05     17     18    475     23      G
06     10     48     29    389      T
07     20     69    361     26      G
08    475      0      0      0      A
09     83    100     40    253      t
10     86     88     59    243      t
11     20     21    223    212      k
12    131    344      0     46      m
13    250     21     54    225      w
14    203      0     10    475      W
15    475     10      0     71      A
16    475      0      0     41      A
17    475      0     15     48      A
18    105    272     75     23      c
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
TBX21_TF2 (T-box)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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