DNA Binding Motif

Accessions: GCM1_CEBPB_1 (HumanTF2 1.0)
Names: GCM1_CEBPB
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: ATGcGGGyrkrTTGCGYAAy
Weblogo:
PSSM: P0 A C G T
01 1484 165 235 19 A
02 114 81 57 1484 T
03 361 24 1123 0 G
04 290 1164 320 137 c
05 212 172 1484 161 G
06 0 28 1484 33 G
07 0 32 1484 10 G
08 227 413 7 836 y
09 632 142 411 299 r
10 192 353 397 541 k
11 723 107 682 0 r
12 0 3 2 1484 T
13 0 0 14 1484 T
14 285 5 1199 8 G
15 0 1484 0 32 C
16 33 10 1484 34 G
17 0 1096 0 388 Y
18 1484 22 7 0 A
19 1484 0 14 7 A
20 6 685 101 692 y
Type: Heterodimer
Binding TFs: CEBPB_TF2 (bZIP transcription factor, Basic region leucine zipper)
GCM1_TF1 (GCM motif protein)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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