DNA Binding Motif

						

			
Accessions: GCM2_EOMES (HumanTF2 1.0)

			
Names: GCM2_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: rTGCGGGhagGTGtga
Weblogo: 
PSSM: P0      A      C      G      T
01   2048    476    897     47      r
02     26    198    195   2946      T
03    743     50   2946     30      G
04    215   2946    404    335      C
05    445      0   2946     75      G
06     17      0   2946     11      G
07     27     28   2946      0      G
08    784    784     93   1285      h
09   2946    270    709   1130      a
10   1361    779   2946    801      g
11     74    100   2946    475      G
12     75    347    145   2946      T
13     67     27   2946    255      G
14    488    455    219   1783      t
15    416    588   1259    683      g
16   1989     28    545    383      a
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
GCM2_TF1 (GCM motif protein)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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