DNA Binding Motif

Accessions: HOXB2_SOX15_2 (HumanTF2 1.0)
Names: HOXB2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 17
Consensus: ACAAwrsravsymATtA
Weblogo:
PSSM: P0 A C G T
01 367 18 17 18 A
02 0 367 1 51 C
03 367 15 27 19 A
04 367 7 10 11 A
05 116 5 10 251 w
06 145 27 222 36 r
07 104 153 214 41 s
08 112 89 104 62 r
09 135 88 62 82 a
10 94 115 92 66 v
11 75 115 120 56 s
12 52 207 59 160 y
13 240 127 78 32 m
14 367 37 34 0 A
15 0 11 8 367 T
16 56 127 38 367 t
17 367 4 58 51 A
Type: Heterodimer
Binding TFs: HOXB2_TF1 (Homeobox domain)
SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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