DNA Binding Motif

Accessions: HOXD12_FIGLA (HumanTF2 1.0)
Names: HOXD12_FIGLA
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: gymrTwAaaakmCAssTGk
Weblogo:
PSSM: P0 A C G T
01 136 97 341 38 g
02 46 184 19 254 y
03 213 224 79 97 m
04 210 44 228 35 r
05 0 0 0 438 T
06 438 57 21 294 w
07 438 22 9 51 A
08 438 91 40 91 a
09 209 49 73 107 a
10 137 106 109 86 a
11 108 93 127 110 k
12 119 134 86 99 m
13 7 438 25 4 C
14 438 0 30 3 A
15 3 183 255 0 s
16 16 238 199 16 s
17 0 17 0 438 T
18 1 0 438 0 G
19 58 53 193 134 k
Type: Heterodimer
Binding TFs: FIGLA_TF2 (Helix-loop-helix DNA-binding domain)
HOXD12_TF1 (Homeobox domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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