DNA Binding Motif

Accessions: GCM1_ELF1_2 (HumanTF2 1.0)
Names: GCM1_ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: kvCGGAArTGckGGt
Weblogo:
PSSM: P0 A C G T
01 226 197 387 395 k
02 313 302 533 57 v
03 278 927 46 16 C
04 6 0 1205 20 G
05 14 0 1205 73 G
06 1205 53 54 87 A
07 1205 56 100 146 A
08 803 49 403 0 r
09 42 62 72 1205 T
10 313 39 1205 3 G
11 378 1205 210 156 c
12 127 20 757 448 k
13 0 11 1205 73 G
14 22 5 1205 21 G
15 45 295 226 639 t
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
GCM1_TF1 (GCM motif protein)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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