DNA Binding Motif

						

			
Accessions: ETV2_SOX15_2_3_4 (HumanTF2 1.0)

			
Names: ETV2_SOX15
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: aCCGGAWryvrwraACAAwrs
Weblogo: 
PSSM: P0      A      C      G      T
01    950    176    405    416      a
02     98   1146    210     49      C
03    234   1356      9      0      C
04      0      0   1356      0      G
05      0      5   1356      6      G
06   1356      8      5      3      A
07    957     24     14    399      W
08    557     22    756     22      r
09     83    584     96    593      y
10    342    369    361    284      v
11    416    300    407    234      r
12    530    258    162    405      w
13    511    135    401    309      r
14    629    295    254    179      a
15   1356     16     41     82      A
16      0   1356    114    202      C
17   1356     12      0     49      A
18   1356      0     67     61      A
19    757     78     47   1356      w
20    488    168    868    148      r
21    190    379    703     84      s
Type: Heterodimer
Binding TFs: SOX15_TF2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
ETV2_TF1 (Ets-domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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