DNA Binding Motif

						

			
Accessions: POU2F1_EOMES_1 (HumanTF2 1.0)

			
Names: POU2F1_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: wTATkCAgyGtka
Weblogo: 
PSSM: P0      A      C      G      T
01   3738   1139   2194   3909      w
02   1958   2282    545  10980      T
03  10980      0    101    227      A
04    680    172   1032  10980      T
05    928    198   5177   5804      k
06    256  10980    462   1515      C
07  10980    563   3524   1050      A
08    728   1922  10980   3339      g
09    955   4202    608   6778      y
10    793    244  10980    194      G
11   3289   4740   1252  10980      t
12   1511   2523   3701   3246      k
13  10980   1775   4067   3202      a
Type: Heterodimer
Binding TFs: EOMES_TF2 (T-box)
POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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