DNA Binding Motif

						

			
Accessions: ZNF75A_2 (HT-SELEX2 May2017), UN0219.1 (JASPAR 2024)

			
Names: ZNF75A
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 14
Consensus: mGcTTTTCCCACam
Weblogo: 
PSSM: P0      A      C      G      T
01    437    506    186    202      m
02    133    147   1331    259      G
03    498   1331    426     61      c
04     57    122     27   1331      T
05      0      1      0   1331      T
06    109    174    149   1331      T
07      2      1      0   1331      T
08      0   1331      0     19      C
09    165   1331      7     44      C
10      1   1331      0      0      C
11   1331      9      7      7      A
12      4   1331      0      0      C
13    998    333    253    174      a
14    349    537    191    254      m
Type: Heterodimer
Binding TFs: ZNF75A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q96N20 (Zinc finger, C2H2 type, KRAB box, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Q96N20
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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