DNA Binding Motif

Accessions: FOXO1_ETV4_2 (HumanTF2 1.0)
Names: FOXO1_ETV4
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 14
Consensus: rwmAACAGGAwGyr
Weblogo:
PSSM: P0 A C G T
01 53 28 91 6 r
02 55 22 21 89 w
03 92 52 0 28 m
04 144 6 0 0 A
05 144 0 8 0 A
06 2 144 0 11 C
07 144 31 6 0 A
08 20 11 144 14 G
09 5 24 144 14 G
10 144 24 15 22 A
11 144 23 28 66 w
12 29 15 115 7 G
13 8 40 16 81 y
14 67 11 52 15 r
Type: Heterodimer
Binding TFs: ETV4_TF2 (Ets-domain)
FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.