DNA Binding Motif

Accessions: ETV2_DLX3_1 (HumanTF2 1.0)
Names: ETV2_DLX3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 20
Consensus: rcCGGAAryrrsskTAATtr
Weblogo:
PSSM: P0 A C G T
01 1493 140 784 373 r
02 283 1743 533 103 c
03 329 2277 24 3 C
04 15 0 2277 9 G
05 0 4 2277 29 G
06 2277 5 2 2 A
07 2277 75 23 714 A
08 815 115 1344 3 r
09 113 824 187 1154 y
10 683 408 921 264 r
11 718 514 748 296 r
12 569 668 656 384 s
13 505 610 669 493 s
14 536 408 660 672 k
15 417 301 122 2277 T
16 2277 125 354 250 A
17 2277 128 64 81 A
18 204 199 267 2277 T
19 484 421 579 1698 t
20 1156 165 1121 163 r
Type: Heterodimer
Binding TFs: DLX3_TF2 (Homeobox domain)
DLX3_Crystal (Homeobox domain)
DLX3_Full (Homeobox domain, Homeobox protein distal-less-like N terminal )
ETV2_TF1 (Ets-domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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