DNA Binding Motif

						

			
Accessions: FOXO1_ETV7 (HumanTF2 1.0)

			
Names: FOXO1_ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 21
Consensus: vwmAACAGGAmryrcTTCCks
Weblogo: 
PSSM: P0      A      C      G      T
01    467    355    499     27      v
02    410    164    115    557      w
03    409    557      3     75      m
04    967     60      5     11      A
05    967      8     54     12      A
06      7    967     12     69      C
07    967     94     50      0      A
08    101      5    967      6      G
09      5      6    967      2      G
10    872     15      6     74      A
11    468    293     27    179      m
12    381    170    317     98      r
13    185    346    116    319      y
14    429    154    267    116      r
15     65    612     92    197      c
16    223      5    166    967      T
17     74      3     23    967      T
18      4    967      2     27      C
19      8    967      0     44      C
20    109    170    416    272      k
21    128    351    302    187      s
Type: Heterodimer
Binding TFs: FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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