DNA Binding Motif

						

			
Accessions: 1lcc_A (3D-footprint 20231221)

			
Names: Lac Repressor
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: STRUCTURE OF THE COMPLEX OF LAC REPRESSOR HEADPIECE AND AN 11 BASE-PAIR HALF-OPERATOR DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY AND RESTRAINED MOLECULAR DYNAMICS
Length: 8
Consensus: TTGTGAGC
Weblogo: 
PSSM: P0      A      C      G      T
01      1      7      7     81      T
02      7      7      9     73      T
03      0      0     96      0      G
04      0      7      1     88      T
05      0      0     96      0      G
06     96      0      0      0      A
07      7      7     75      7      G
08      7     75      7      7      C
Binding TFs: 1lcc_A (Bacterial regulatory proteins, lacI family)
Binding Sites: 1lcc_B
1lcc_C
			
Publications: Chuprina V.P, Rullmann J.A, Lamerichs R.M, van Boom J.H, Boelens R, Kaptein R. Structure of the complex of lac repressor headpiece and an 11 base-pair half-operator determined by nuclear magnetic resonance spectroscopy and restrained molecular dynamics. Journal of molecular biology 234:446-62 (1993). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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