DNA Binding Motif

						

			
Accessions: 4iqr_EF (3D-footprint 20231221)

			
Names: Hepatocyte nuclear factor 4-alpha
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Multi-Domain Organization of the HNF4alpha Nuclear Receptor Complex on DNA
Length: 12
Consensus: TGACCTnTGACC
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      0      0     96      0      G
03     78      6      6      6      A
04      0     96      0      0      C
05      0     96      0      0      C
06      6      6      6     78      T
07     24     24     24     24      n
08      0      0      0     96      T
09      6      6     78      6      G
10     78      6      6      6      A
11      0     96      0      0      C
12      6     78      6      6      C
Type: Heterodimer
Binding TFs: 4iqr_E (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
4iqr_F (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
Binding Sites: 4iqr_G
4iqr_H
			
Publications: Chandra V, Huang P, Potluri N, Wu D, Kim Y, Rastinejad F. Multidomain integration in the structure of the HNF-4α nuclear receptor complex. Nature 495:394-8 (2013). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.