DNA Binding Motif

Accessions: MYBL1_ONECUT2 (HumanTF2 1.0)
Names: MYBL1_ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 15
Consensus: yAACGgtTATyGAty
Weblogo:
PSSM: P0 A C G T
01 59 274 84 219 y
02 636 0 0 36 A
03 636 19 15 0 A
04 37 636 0 26 C
05 21 95 636 30 G
06 94 74 636 151 g
07 100 117 38 380 t
08 88 53 23 472 T
09 636 62 26 0 A
10 42 63 107 636 T
11 21 451 34 185 y
12 35 86 636 78 G
13 636 22 33 48 A
14 51 136 59 389 t
15 27 289 117 203 y
Type: Heterodimer
Binding TFs: MYBL1_TF1 (Myb-like DNA-binding domain, Myb-like DNA-binding domain)
ONECUT2_TF2 (Homeobox domain, CUT domain)
ONECUT2_Full (Homeobox domain, CUT domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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