DNA Binding Motif

						

			
Accessions: 1osl_B (3D-footprint 20231221)

			
Names: Lactose operon repressor
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Solution structure of a dimeric lactose DNA-binding domain complexed to a nonspecific DNA sequence
Length: 8
Consensus: atwagata
Weblogo: 
PSSM: P0      A      C      G      T
01     52     16     14     14      a
02     19     16     16     45      t
03     27     22     22     25      w
04     63     10     13     10      a
05     13     14     56     13      g
06     38     20     19     19      a
07     21     23     21     31      t
08     38     19     19     20      a
Binding TFs: 1osl_B (Bacterial regulatory proteins, lacI family)
Binding Sites: 1osl_C / 1osl_D
			
Publications: Kalodimos C.G, Biris N, Bonvin A.M, Levandoski M.M, Guennuegues M, Boelens R, Kaptein R. Structure and flexibility adaptation in nonspecific and specific protein-DNA complexes. Science (New York, N.Y.) 305:386-9 (2004). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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