DNA Binding Motif

Accessions: GCM2_MAX (HumanTF2 1.0)
Names: GCM2_MAX
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: aTGcgGGyraCAyGTG
Weblogo:
PSSM: P0 A C G T
01 327 122 130 33 a
02 37 72 112 613 T
03 152 15 461 3 G
04 107 365 87 54 c
05 166 20 613 177 g
06 11 52 613 10 G
07 46 14 613 41 G
08 48 187 42 336 y
09 283 97 171 61 r
10 244 104 149 115 a
11 56 613 20 34 C
12 613 0 32 135 A
13 24 613 125 352 y
14 125 43 613 57 G
15 0 66 81 613 T
16 10 36 613 55 G
Type: Heterodimer
Binding TFs: GCM2_TF1 (GCM motif protein)
MAX_TF2 (Helix-loop-helix DNA-binding domain)
MAX_Full (Helix-loop-helix DNA-binding domain)
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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