DNA Binding Motif

						

			
Accessions: GCM1_ETV7_2 (HumanTF2 1.0)

			
Names: GCM1_ETV7
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: mTrmGGGCGGAaGtgkdtCCssy
Weblogo: 
PSSM: P0      A      C      G      T
01    252    243    129      0      m
02    213     31     37    620      T
03    328     32    292      0      r
04    171    338     60     52      m
05     30    140    620     77      G
06      2      5    620      0      G
07      0      0    620      0      G
08    113    620    124     25      C
09      0      3    620     29      G
10      0      0    620      8      G
11    620      0      0     95      A
12    620    142     55    140      a
13    153     35    620     61      G
14    146    114    125    236      t
15    140     58    330     92      g
16     82     93    222    224      k
17    583    141    488    620      d
18    133      0    224    620      t
19     16    620     32      0      C
20      1    620      4    103      C
21    118    212    192     97      s
22     85    166    309     59      s
23    128    209    100    183      y
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
ETV7_TF1 / ETV7_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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