DNA Binding Motif

						

			
Accessions: MEIS1_ELF1 (HumanTF2 1.0)

			
Names: MEIS1_ELF1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 12
Consensus: vTGmCGGAAgyr
Weblogo: 
PSSM: P0      A      C      G      T
01   1581   1582   1251    581      v
02    441    513    179   4995      T
03    348    381   4995    152      G
04   2046   4995    165    797      m
05    135   4995      7      4      C
06     54      1   4995      3      G
07      0      0   4995      0      G
08   4995     27      0    100      A
09   4995     98     12    403      A
10   1200   1074   4995    154      g
11   1183   2365    838   4995      y
12   1366   1060   1503   1066      r
Type: Heterodimer
Binding TFs: ELF1_TF2 (Ets-domain, Transcription factor protein N terminal)
MEIS1_TF1 (Homeobox domain, Homeobox KN domain)
MEIS1_Crystal (Homeobox domain, Homeobox KN domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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