DNA Binding Motif

						

			
Accessions: 5zmc_B (3D-footprint 20231221)

			
Names: Protein C-ets-1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structural Basis for Reactivation of -146C>T Mutant TERT Promoter by cooperative binding of p52 and ETS1/2
Length: 6
Consensus: CTTCCG
Weblogo: 
PSSM: P0      A      C      G      T
01     11     67      9      9      C
02      9     11      9     67      T
03      0      0      0     96      T
04      0     96      0      0      C
05      0     96      0      0      C
06     11      9     67      9      G
Binding TFs: 5zmc_B (Ets-domain)
Binding Sites: 5zmc_C
5zmc_D
			
Publications: Xu X, Li Y, Bharath SR, Ozturk MB, Bowler MW, Loo BZL, Tergaonkar V, Song H. Structural basis for reactivating the mutant TERT promoter by cooperative binding of p52 and ETS1. Nat Commun 9:3183 (2018). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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