DNA Binding Motif

						

			
Accessions: ATF3_4 (HT-SELEX2 May2017), MA0605.2 (JASPAR 2024)

			
Names: ATF3
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 12
Consensus: grTGACGTCAyc
Weblogo: 
PSSM: P0      A      C      G      T
01   8505   8220  16894   6926      g
02  24741   1354  15805      0      r
03      0      0      1  40546      T
04      0      0  40546   1366      G
05  40546      0      0      0      A
06      0  40546      0    556      C
07    891      0  40546      0      G
08      0      0      0  40546      T
09   1520  40546      0      0      C
10  40546      0      0      0      A
11      0  15737   1094  24808      y
12   6919  16820   8242   8564      c
Type: Heterodimer
Binding TFs: P18847 (bZIP transcription factor, Basic region leucine zipper)
ATF3 (bZIP transcription factor, Basic region leucine zipper)
P18847
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]


Wang J., Cao Y., Steiner D. F. Regulation of proglucagon transcription by activated transcription factor (ATF) 3 and a novel isoform, ATF3b, through the cAMP-response element/ATF site of the proglucagon gene promoter. J. Biol. Chem. 278:32899-32904 (2003). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.