DNA Binding Motif

						

			
Accessions: ALX4_EOMES (HumanTF2 1.0)

			
Names: ALX4_EOMES
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 23
Consensus: skyGctAAytwwwktTvrCACmt
Weblogo: 
PSSM: P0      A      C      G      T
01   1410   2030   2102    191      s
02   1273   1756   5733   3279      k
03     45   2474    182   3259      y
04     51      3   5733     34      G
05    890   4030    221   1703      c
06   1109    740   1196   5733      t
07   5733      0    159    350      A
08   5733    296    394    296      A
09   1038   2013    344   3720      y
10   1349    717    690   2977      t
11   2797    927    388   1621      w
12   2051    856    757   2070      w
13   2212    808    754   1958      w
14    992   1276   1589   1876      k
15   1228    870    601   3034      t
16    232    507    144   5733      T
17   1650   1486   1450   1147      v
18   5733    172   2448   1134      r
19     16   5733      0      4      C
20   5733     74   1749     66      A
21   1162   5733    803    582      C
22   1435   2682    417   1199      m
23    801   1357     59   3516      t
Type: Heterodimer
Binding TFs: ALX4_TF2 (Homeobox domain)
EOMES_TF2 (T-box)
ALX4_TF1 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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