DNA Binding Motif

						

			
Accessions: HOXD12_HOXA3_1 (HumanTF2 1.0)

			
Names: HOXD12_HOXA3
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 16
Consensus: yTaAtkrsYmATAAAm
Weblogo: 
PSSM: P0      A      C      G      T
01    201    622    200    416      y
02    219     65     39   1439      T
03   1439     67    199    486      a
04   1439     70     56    116      A
05    166    150    493   1439      t
06     57    183    609    830      k
07    455     44    985     29      r
08    408    630    809     77      s
09     18    388     20   1013      Y
10    887    552    252    151      m
11   1105     41    334    127      A
12     17      0     21   1439      T
13   1439    132      0    347      A
14   1439     12      1    173      A
15   1439    188     48    173      A
16    567    412    246    215      m
Type: Heterodimer
Binding TFs: HOXD12_TF1 (Homeobox domain)
HOXA3_TF1 / HOXA3_TF2 (Homeobox domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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