DNA Binding Motif

						

			
Accessions: POU2F1_TBX21_2 (HumanTF2 1.0)

			
Names: POU2F1_TBX21
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: wTATkCAGyGywa
Weblogo: 
PSSM: P0      A      C      G      T
01   2935    286    655   1753      w
02    907    964    196   5629      T
03   5629      0      0      0      A
04    216      0    272   5629      T
05    299      5   2762   2867      k
06    103   5629     59    682      C
07   5629    135    671    381      A
08    216    753   5629    446      G
09    246   1689     46   3940      y
10    309      0   5629     84      G
11   1104   2588    488   5629      y
12   1499    824   1104   2203      w
13   5629    422   1252   1048      a
Type: Heterodimer
Binding TFs: POU2F1_TF1 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
TBX21_TF2 (T-box)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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