DNA Binding Motif

Accessions: UP00005A_1 (UniPROBE 20160601)
Names: Activating enhancer-binding protein 2 alpha, Activator protein 2, alpha, Ap-2 (a), AP-2 alpha, AP2-alpha, Ap2tf, Tcfap2a, Tfap2a, transcription factor AP-2, Transcription factor AP-2 alpha
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 15
Consensus: wwtsCCysrGGsraa
Weblogo:
PSSM: P0 A C G T
01 0.42 0.10 0.12 0.35 w
02 0.25 0.17 0.20 0.38 w
03 0.23 0.23 0.07 0.47 t
04 0.01 0.50 0.46 0.02 s
05 0.01 0.99 0 0 C
06 0 0.86 0 0.14 C
07 0.01 0.32 0.19 0.49 y
08 0.04 0.38 0.50 0.09 s
09 0.49 0.19 0.32 0.01 r
10 0.14 0 0.86 0 G
11 0 0 0.99 0.01 G
12 0.02 0.46 0.50 0.01 s
13 0.35 0.09 0.42 0.14 r
14 0.56 0.13 0.13 0.17 a
15 0.33 0.20 0.24 0.23 a
Binding TFs: UP00005A (Transcription factor AP-2)
Binding Sites: CCCCAGGC
CCCCAGGG
CCCCCAGG
CCCCCGGG
CCCCGAGG
CCCCGGGC
CCCCGGGG
CCCGAGGG
CCCGCGGG
CCCGGGGC
CCCTCAGG
CCCTGAGG
CCGCAGGC
CCGGAGGC
CCGGGGGC
CCTCAGGC
CCTCCGGC
CCTCGGGC
CCTGAGGC
CCTGGGGC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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