DNA Binding Motif

						

			
Accessions: MA1965.1 (JASPAR 2024)

			
Names: SP5
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 10
Consensus: cyCCTCCCcs
Weblogo: 
PSSM: P0      A      C      G      T
01   2573  10436   3624   4063      c
02   2297   8101   4560   5738      y
03      6  20683      3      4      C
04      7  20286    403      0      C
05      0      0    231  20465      T
06     47  20649      0      0      C
07     11  20451    234      0      C
08      0  20604     92      0      C
09   5142   7068   3372   5114      c
10   2875   8246   5620   3955      s
Type: Heterodimer
Binding TFs: Q6BEB4 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q6BEB4
Binding Sites: MA1965.1.1 / MA1965.1.11 / MA1965.1.12 / MA1965.1.17 / MA1965.1.19
MA1965.1.10 / MA1965.1.9
MA1965.1.10 / MA1965.1.11
MA1965.1.13 / MA1965.1.14
MA1965.1.14 / MA1965.1.16
MA1965.1.15 / MA1965.1.17
MA1965.1.16 / MA1965.1.18
MA1965.1.18 / MA1965.1.19 / MA1965.1.20
MA1965.1.2
MA1965.1.20
MA1965.1.3
MA1965.1.4
MA1965.1.5
MA1965.1.6
MA1965.1.7
MA1965.1.7 / MA1965.1.8
MA1965.1.8 / MA1965.1.9
MA1965.1.12
MA1965.1.13
MA1965.1.15
			
Publications: Huggins IJ, Bos T, Gaylord O, Jessen C, Lonquich B, Puranen A, Richter J, Rossdam C, Brafman D, Gaasterland T, Willert K. The WNT target SP5 negatively regulates WNT transcriptional programs in human pluripotent stem cells. Nat Commun 8:1034 (2017). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.