DNA Binding Motif

						

			
Accessions: HOXB2_HOXB13_1 (HumanTF2 1.0)

			
Names: HOXB2_HOXB13
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: ymATCATCGTWAA
Weblogo: 
PSSM: P0      A      C      G      T
01     57    253     52    410      y
02    287    387     77     21      m
03    772     11      3     10      A
04      0     32      0    772      T
05     32    772     58    251      C
06    772    115     46      0      A
07     38    191     80    772      T
08      0    708      0     86      C
09    225     15    772     40      G
10      0     16      1    772      T
11    772      5     23    271      W
12    772      0      1      9      A
13    772     80      7      0      A
Type: Heterodimer
Binding TFs: HOXB13_TF1 / HOXB13_TF2 (Homeobox domain)
HOXB2_TF1 (Homeobox domain)
HOXB13_Full (Homeobox domain, Hox protein A13 N terminal)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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